highlight_01

Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.

Zika virus (ZIKV) is an emerging pathogen that causes devastating congenital defects. The overlapping epidemiology and immunologic cross-reactivity between ZIKV and dengue virus (DENV) pose complex challenges to vaccine design, given the potential for antibody-dependent enhancement of disease. Therefore, classification of ZIKV-specific antibody targets is of notable value...

  • Authors: Rajeshwer S Sankhala, Vincent Dussupt, Gina Donofrio, Gregory D Gromowski, Rafael A De La Barrera, Rafael A Larocca, Letzibeth Mendez-Rivera, Anna Lee, Misook Choe, Weam Zaky, Grace Mantus, Jaime L Jensen, Wei-Hung Chen, Neelakshi Gohain, Hongjun Bai, Michael K McCracken, Rosemarie D Mason, David Leggat, Bonnie M Slike, Ursula Tran, Ningbo Jian, Peter Abbink, Rebecca Peterson, Eric Araujo Mendes, Rafael Freitas de Oliveira Franca, Guilherme Amaral Calvet, Ana Maria Bispo de Filippis, Adrian McDermott, Mario Roederer, Mayda Hernandez, Amie Albertus, Edgar Davidson, Benjamin J Doranz, Morgane Rolland, Merlin L Robb, Rebecca M Lynch, Dan H Barouch, Richard G Jarman, Stephen J Thomas, Kayvon Modjarrad, Nelson L Michael, Shelly J Krebs, M Gordon Joyce.
  • Cell Rep. 2023 Aug 29;42(8):112942. doi: 10.1016/j.celrep.2023.112942. Epub 2023 Aug 9.